Supplementary Figure 8 from Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents

Authors :: Scott Kopetz
Michael A. Davies
Gary E. Gallick
Jayesh Desai
Garth Powis
Gordon B. Mills
Gideon Bollag
William G. Bornman
Xi M. Tang
Ignacio I. Wistuba
Zhi-Qin Jiang
Y.N. Vashisht Gopal
Farshid Dayyani
Robert Lemos
Chun C. Tsao
John M. Mariadason
Feng Tian
Muling Mao
Publication Year :: 2023
Publisher :: American Association for Cancer Research (AACR), 2023.
Abstract: PDF file - 39K, HT29 PLX4720 resistant clone was treated with EGFR siRNA for 48 h, and then treated with 1�M PLX4720 for further two weeks. EGFR knockdown reduced sensitivity to PLX4720 by numbers of formed colonies (# P

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