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Magnetic Nanoparticles in Cancer Therapy and Diagnosis
- Source :
- Adv Healthc Mater
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- There is urgency for the development of nanomaterials that can meet emerging biomedical needs. Magnetic nanoparticles (MNPs) offer high magnetic moments and surface-area-to-volume ratios that make them attractive for hyperthermia therapy of cancer and targeted drug delivery. Additionally, they can function as contrast agents for magnetic resonance imaging (MRI) and can improve the sensitivity of biosensors and diagnostic tools. Recent advancements in nanotechnology have resulted in the realization of the next generation of MNPs suitable for these and other biomedical applications. This review discusses methods utilized for the fabrication and engineering of MNPs. Recent progress in the use of MNPs for hyperthermia therapy, controlling drug release, MRI, and biosensing is also critically reviewed. Finally, challenges in the field and potential opportunities for the use of MNPs toward improving their properties are discussed.
- Subjects :
- Computer science
medicine.medical_treatment
Biomedical Engineering
Cancer therapy
Contrast Media
Pharmaceutical Science
Nanotechnology
02 engineering and technology
Cancer detection
010402 general chemistry
Diagnostic tools
01 natural sciences
Article
Biomaterials
Magnetics
Drug Delivery Systems
Neoplasms
medicine
Humans
Magnetite Nanoparticles
021001 nanoscience & nanotechnology
Magnetic Resonance Imaging
Hyperthermia therapy
0104 chemical sciences
Targeted drug delivery
Drug delivery
Drug release
Magnetic nanoparticles
0210 nano-technology
Subjects
Details
- ISSN :
- 21922659 and 21922640
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Advanced Healthcare Materials
- Accession number :
- edsair.doi.dedup.....4c995f671e8748cbafc0d12eb4831afd