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Increasing incidence of anaphylaxis in Hong Kong from 2009 to 2019—discrepancies of anaphylaxis care between adult and paediatric patients
- Source :
- Clinical and Translational Allergy
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- Background Anaphylaxis has been increasing in developed countries but there is very little published data on the burden of anaphylaxis and the pattern of adrenaline autoinjector (AAI) prescription from Asia. We aim to determine the incidence rates of anaphylaxis and prescription rates of AAI over the past decade in Hong Kong. Methods Using a centralized electronic database of Hong Kong’s sole public-funded healthcare provider, we obtained and analysed all patients between 2009 and 2019 with physician-reported diagnosis of anaphylaxis. Incidence rates were calculated using population statistics as the denominator. Patients’ prescriptions on discharge were collected to determine the AAI prescription rates. Results The overall 10-year estimated incidence rate of anaphylaxis was 3.57 per 100,000 person-years. An increasing trend over time across both paediatric and adult populations from 2009 to 2014 was found, which remained stable until 2019. This was more marked among the paediatric population (paediatric vs adult incidence rate ratio in 2019: 3.51 [95% CI 1.12–2.66] vs 1.82 [95% CI 1.05–1.60]). There was an overall increasing rate of AAI prescription for patients admitted for anaphylaxis, but the overall AAI prescription rate was less than 15% and was significantly less likely to be prescribed for the adult compared to paediatric patients (36.5% vs. 89.4%, p Conclusions An increasing trend of anaphylaxis incidence rates over the past decade is evident in Asian populations, with a discrepantly low rate of AAI prescription, particularly in the adult patients.
- Subjects :
- Pulmonary and Respiratory Medicine
medicine.medical_specialty
Allergy
Pediatrics
Epidemiology
Immunology
Rate ratio
03 medical and health sciences
0302 clinical medicine
Autoinjector
Adrenaline autoinjector
Immunology and Allergy
Medicine
Medical prescription
Anaphylaxis
030201 allergy
business.industry
Research
Incidence
Incidence (epidemiology)
medicine.disease
030228 respiratory system
business
Developed country
Subjects
Details
- ISSN :
- 20457022
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Clinical and Translational Allergy
- Accession number :
- edsair.doi.dedup.....4c93cf74c3521418228df662613a2dca