Sorting Out Fate Determination

Authors :: Heiko Lickert
Mostafa Bakhti
Aimée Bastidas-Ponce
Source :: Dev. Cell 49, 1-3 (2019)
Publication Year :: 2019
Abstract: How organ morphogenesis specifies cell fate and whether organ progenitors are predetermined or specified via niche signals are critical developmental biology questions. In this issue of Developmental Cell, Nyeng et al. (2019) modulate cell-cell adhesion in the pancreas and provide evidence that progenitors are plastic and instructed by niche signals.

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