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The influence of genetic polymorphisms on performance and cardiac and hemodynamic parameters among Brazilian soccer players
- Source :
- Scopus, Repositório Institucional da UNESP, Universidade Estadual Paulista (UNESP), instacron:UNESP
- Publication Year :
- 2017
-
Abstract
- Made available in DSpace on 2018-12-11T16:47:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01 Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) This study investigated whether ACTN3 R577X, AMPD1 C34T, I/D ACE, and M235T AGT polymorphisms can affect performance tests such as jumping, sprinting, and endurance in 220 young male athletes from professional minor league soccer team from São Paulo Futebol Clube, Brazil. I/D ACE and M235T AGT polymorphisms were also analyzed according to cardiac and hemodynamic parameters. Athletes were grouped or not by age. DNA from saliva and Taqman assays were used for genotyping 220 athletes and the results were associated with performance tests. Ventricle mass, ventricle end-diastolic diameter, enddiastolic volume, and ejection fraction were assessed by echocardiogram. Arterial pressure, heart rate, and oximetry were assessed by a cardioscope. The main results of this study were that athletes who carried RR/RX (ACTN3) and DD (ACE) genotypes presented better performance during jump and sprint tests. On the other hand, athletes with ID/II genotype presented better results during endurance test, while AGT genotypes did not seem to favor the athletes during the evaluated physical tests. CC genotype (AMPD1) only favored the athletes during 10-m sprint test. Although there are environmental interactions influencing performance, the present results suggest that RR/RX ACTN3 and ACE DD genotypes may benefit athletes in activities that require strength and speed, while II ACE genotype may benefit athletes in endurance activities. This information could help coaches to plan the training session to improve the athletes’ performance. Joint Graduate Program in Physiological Sciences PIPGCF UFSCar/UNESP Bauru School of Dentistry University of São Paulo State University of Campinas Institute of Bioscience University of São Paulo State (UNESP) Physiological Sciences PIPGCF UFSCar/UNESP Joint Graduate Program in Physiological Sciences PIPGCF UFSCar/UNESP Institute of Bioscience University of São Paulo State (UNESP) Physiological Sciences PIPGCF UFSCar/UNESP CNPq: 140206/2011-6 FAPESP: 2011/21586-8
- Subjects :
- Male
Genotyping Techniques
Physiology
Endocrinology, Diabetes and Metabolism
Angiotensinogen
Hemodynamics
030204 cardiovascular system & hematology
medicine.disease_cause
AMP Deaminase
0302 clinical medicine
Jumping
ACE and AGT polymorphisms
Medicine
Actinin
Nutrition and Dietetics
Ejection fraction
biology
Soccer athletes’ performance
General Medicine
Sprint
Cardiology
Cardiac and hemodynamic parameters
Brazil
Adult
medicine.medical_specialty
Adolescent
Athletic Performance
Peptidyl-Dipeptidase A
AMPD1
ACTN3
03 medical and health sciences
Young Adult
Physiology (medical)
Internal medicine
Heart rate
Soccer
Humans
Genotyping
Life Style
Polymorphism, Genetic
business.industry
Athletes
030229 sport sciences
Sequence Analysis, DNA
biology.organism_classification
Blood pressure
Physical therapy
business
Subjects
Details
- ISSN :
- 17155320
- Volume :
- 42
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
- Accession number :
- edsair.doi.dedup.....4c15dadc382ff35b9760852df5aab21b