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Etiology of Sudden Cardiac Arrest in Patients with Epilepsy: Experience of Tertiary Referral Hospital in Sapporo City, Japan
- Source :
- Neurologia medico-chirurgica
- Publication Year :
- 2016
- Publisher :
- Japan Neurosurgical Society, 2016.
-
Abstract
- It has been reported that epilepsy patients had higher risk of sudden death than that of the general population. However, in Japan, there is very little literature on the observational research conducted on sudden fatal events in epilepsy. We performed a single-center, retrospective study on all the out-of-hospital cardiac arrest (OHCA) patients treated in our emergency department between 2007 and 2013. Among the OHCA patients, we extracted those with a history of epilepsy and then analyzed the characteristics of the fatal events and the background of epilepsy. From 1,823 OHCA patients, a total of 10 cases were enrolled in our study. The median age was 34 years at the time of the incident [9–52 years; interquartile range (IQR), 24–45]. We determined that half of our cases resulted from external causes of death such as drowning and suffocation and the other half were classified as sudden unexpected death in epilepsy (SUDEP). In addition, asphyxia was implicated as the cause in eight cases. Only the two near-drowning patients were immediately resuscitated, but the remaining eight patients died. The median age of first onset of epilepsy was 12 years (0.5–30; IQR, 3–21), and the median disease duration was 25 years (4–38; IQR, 6–32). Patients with active epilepsy accounted for half of our series and they were undergoing poly anti-epileptic drug therapy. The fatal events related to epilepsy tended to occur in the younger adult by external causes. An appropriate therapeutic intervention and a thorough observation were needed for its prevention.
- Subjects :
- Adult
Male
Pediatrics
medicine.medical_specialty
Adolescent
suffocation
Population
cardiac arrest
Sudden death
Tertiary Care Centers
Asphyxia
Young Adult
03 medical and health sciences
Epilepsy
0302 clinical medicine
Japan
Interquartile range
Cause of Death
medicine
Humans
030212 general & internal medicine
Child
education
Retrospective Studies
Cause of death
sudden unexpected death in epilepsy
education.field_of_study
Drowning
business.industry
Sudden cardiac arrest
Emergency department
Middle Aged
medicine.disease
Death, Sudden, Cardiac
Anesthesia
Female
Original Article
Surgery
Neurology (clinical)
medicine.symptom
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 13498029 and 04708105
- Volume :
- 56
- Database :
- OpenAIRE
- Journal :
- Neurologia medico-chirurgica
- Accession number :
- edsair.doi.dedup.....4bee38d34b5ada18eccd1721886c3568
- Full Text :
- https://doi.org/10.2176/nmc.oa.2015-0285