Back to Search
Start Over
COVID-19 Severity is Tripled in the Diabetes Community: A Prospective Analysis of the Pandemic’s Impact in Type 1 and Type 2 Diabetes
- Source :
- Diabetes care, vol 44, iss 2, Diabetes Care
- Publication Year :
- 2020
- Publisher :
- American Diabetes Association, 2020.
-
Abstract
- OBJECTIVE To quantify and contextualize the risk for coronavirus disease 2019 (COVID-19)–related hospitalization and illness severity in type 1 diabetes. RESEARCH DESIGN AND METHODS We conducted a prospective cohort study to identify case subjects with COVID-19 across a regional health care network of 137 service locations. Using an electronic health record query, chart review, and patient contact, we identified clinical factors influencing illness severity. RESULTS We identified COVID-19 in 6,138, 40, and 273 patients without diabetes and with type 1 and type 2 diabetes, respectively. Compared with not having diabetes, people with type 1 diabetes had adjusted odds ratios of 3.90 (95% CI 1.75–8.69) for hospitalization and 3.35 (95% CI 1.53–7.33) for greater illness severity, which was similar to risk in type 2 diabetes. Among patients with type 1 diabetes, glycosylated hemoglobin (HbA1c), hypertension, race, recent diabetic ketoacidosis, health insurance status, and less diabetes technology use were significantly associated with illness severity. CONCLUSIONS Diabetes status, both type 1 and type 2, independently increases the adverse impacts of COVID-19. Potentially modifiable factors (e.g., HbA1c) had significant but modest impact compared with comparatively static factors (e.g., race and insurance) in type 1 diabetes, indicating an urgent and continued need to mitigate severe acute respiratory syndrome coronavirus 2 infection risk in this community.
- Subjects :
- Male
Research design
medicine.medical_specialty
Diabetic ketoacidosis
Endocrinology, Diabetes and Metabolism
Comorbidity
Type 2 diabetes
Severity of Illness Index
Medical and Health Sciences
Endocrinology & Metabolism
Clinical Research
Diabetes mellitus
Internal medicine
Severity of illness
Diabetes Mellitus
Odds Ratio
Internal Medicine
medicine
Humans
Electronic Health Records
Prospective Studies
Pathophysiology/Complications
Metabolic and endocrine
Advanced and Specialized Nursing
Type 1 diabetes
business.industry
Prevention
Diabetes
COVID-19
Odds ratio
Middle Aged
medicine.disease
Hospitalization
Infectious Diseases
Good Health and Well Being
Hypertension
Female
business
Type 2
Type 1
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Diabetes care, vol 44, iss 2, Diabetes Care
- Accession number :
- edsair.doi.dedup.....4be93bdd081bcdbfbd30e3968951ffc3
- Full Text :
- https://doi.org/10.2337/figshare.13235066