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Antidiuretic Hormone Following Surgery in Children
- Source :
- Acta Paediatrica. 79:461-466
- Publication Year :
- 1990
- Publisher :
- Wiley, 1990.
-
Abstract
- We studied 13 children subjected to elective tonsillectomy, 6 of whom (study patients) received supplemental intravenous isotonic saline during and after operation, and 7 of whom (controls) did not. Clinical and biochemical evidence of hypovolaemia was present in the control but not in the study patients. Plasma antidiuretic hormone (ADH) and urine osmolality were higher in controls (p less than 0.005 and p less than 0.05 respectively). Plasma sodium concentration and osmolality were similar in the two groups. We conclude that hypovolaemia is the principal stimulus to ADH release following surgery and that, in addition to replacement of observed losses of blood and other fluids by fluids of appropriate composition, hypovolaemia should be prevented by the administration of maintenance quantities of isotonic fluid, rather than exacerbated by fluid restriction, in patients in whom oral fluid intake is interrupted for more than a brief period. Hypotonic and sodium free fluids should be avoided because of the risk of hyponatraemia.
- Subjects :
- medicine.medical_specialty
Vasopressin
Vasopressins
Sodium Chloride
Peptide hormone
Catecholamines
Postoperative Complications
Hypovolemia
Internal medicine
medicine
Humans
Plasma Volume
Child
Tonsillectomy
Dehydration
business.industry
General Medicine
medicine.disease
Surgery
Endocrinology
Child, Preschool
Surgical Procedures, Operative
Pediatrics, Perinatology and Child Health
Urine osmolality
Fluid Therapy
Tonicity
Isotonic Solutions
medicine.symptom
Hyponatremia
business
Antidiuretic
Subjects
Details
- ISSN :
- 16512227 and 08035253
- Volume :
- 79
- Database :
- OpenAIRE
- Journal :
- Acta Paediatrica
- Accession number :
- edsair.doi.dedup.....4bb01cb7b74f2cd144439e178c5a95e7