Influence of amphotericin B and amphotericin B colloidal dispersion on the functions of human phagocytes in defence against Aspergillus species

Authors :: Cornelia Speth
Cornelia Lass-Flörl
M. P. Dierich
Susanne Perkhofer
Gerhard Blum
Astrid Mayr
Source :: European Journal of Clinical Microbiology & Infectious Diseases. 26:413-417
Publication Year :: 2007
Publisher :: Springer Science and Business Media LLC, 2007.
Abstract: This study investigated the in vitro effects of amphotericin B and amphotericin B colloidal dispersion (ABCD) on phagocytosis and inhibition of germination of clinical isolates of Aspergillus spp. by monocyte-derived macrophages (MDMs).Both amphotericin B and ABCD caused significant reductions in uptake of conidia of Aspergillus spp. by MDMs (p

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