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Serological survey of hepatitis B immunity in healthcare workers in Catalonia (Spain)
Serological survey of hepatitis B immunity in healthcare workers in Catalonia (Spain)
- Source :
- Human Vaccines & Immunotherapeutics. 13:435-439
- Publication Year :
- 2016
- Publisher :
- Informa UK Limited, 2016.
-
Abstract
- Healthcare workers (HCW) are exposed to preventable infectious diseases, notably hepatitis B (HB). The aim of this study was to determine the immunity of HCW against hepatitis B. We made a seroprevalence study using a self-administered survey and obtained blood samples. Antibodies against the HB surface antigen (anti-HBs) and against the HB core antigen (anti-HBc) were studied. The odds ratio (OR) and 95% confidence intervals (CI) were calculated. The adjusted OR were calculated using logistic regression. Of the 644 HCW who participated (29.7% physicians, 38.7% nurses, 13.4% other clinical workers and 18.3% non-clinical workers), 46.4% were primary care workers and 53.6% hospital workers. The overall prevalence of anti-HBs was 64.4%. HCW aged25 y had a significantly higher prevalence (86.7%) than those aged 35-44 y (adjusted OR 3.40; 95% CI 1.06-10.90). The prevalence of anti-HBc was 4.1%, and increased with age. Significant differences were found for HCW aged44 y with respect to those aged 25-34 y. 75.6% of HCW stated they were vaccinated, but only 39.3% had a vaccination card. In HCW who stated they were unvaccinated, 10.8% had a vaccinated serological pattern (anti-HBc-negative and anti-HBs -positive). Written, updated vaccination records are essential to reliably determine the vaccination status.
- Subjects :
- Adult
Male
0301 basic medicine
medicine.medical_specialty
Health Personnel
education
030106 microbiology
Immunology
Serology
Young Adult
03 medical and health sciences
0302 clinical medicine
Seroepidemiologic Studies
Surveys and Questionnaires
Internal medicine
Health care
medicine
Humans
Immunology and Allergy
Seroprevalence
030212 general & internal medicine
Hepatitis B Antibodies
Aged
Pharmacology
Hepatitis B Surface Antigens
biology
business.industry
Age Factors
Odds ratio
Middle Aged
Hepatitis B
medicine.disease
Hepatitis B Core Antigens
Research Papers
Confidence interval
Vaccination
Cross-Sectional Studies
Spain
biology.protein
Female
Antibody
business
Subjects
Details
- ISSN :
- 2164554X and 21645515
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- Human Vaccines & Immunotherapeutics
- Accession number :
- edsair.doi.dedup.....4b719e234e950ef74150a9393de1e06a
- Full Text :
- https://doi.org/10.1080/21645515.2017.1264791