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The effect of the 7R allele at the DRD4 locus on risk tolerance is independent of background risk in Senegalese fishermen
- Source :
- Scientific Reports, Scientific Reports, 2023, 13 (1), pp.622. ⟨10.1038/s41598-022-27002-3⟩
- Publication Year :
- 2023
- Publisher :
- HAL CCSD, 2023.
-
Abstract
- It has been shown that living in risky environments, as well as having a risky occupation, can moderate risk-tolerance. Despite the involvement of dopamine in the expectation of reward described by neurobiologists, a GWAS study was not able to demonstrate a genetic contribution of genes involved in the dopaminergic pathway in risk attitudes and gene candidate studies gave contrasting results. We test the possibility that a genetic effect of the DRD4-7R allele in risk-taking behavior could be modulated by environmental factors. We show that the increase in risk-tolerance due to the 7R allele is independent of the environmental risk in two populations in Northern Senegal, one of which is exposed to a very high risk due to dangerous fishing.
- Subjects :
- Multidisciplinary
economic games
[SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]
[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics
[SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior
[SDV]Life Sciences [q-bio]
Local adaptation
[SHS.ANTHRO-BIO]Humanities and Social Sciences/Biological anthropology
dopamine receptor
population genetics
JEL: Z - Other Special Topics/Z.Z1 - Cultural Economics • Economic Sociology • Economic Anthropology/Z.Z1.Z13 - Economic Sociology • Economic Anthropology • Social and Economic Stratification
[SHS.ECO]Humanities and Social Sciences/Economics and Finance
behaviour
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Database :
- OpenAIRE
- Journal :
- Scientific Reports, Scientific Reports, 2023, 13 (1), pp.622. ⟨10.1038/s41598-022-27002-3⟩
- Accession number :
- edsair.doi.dedup.....4b4bd19acad087e0122d0e6c47c0d96f