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Perspective: The promise of multi-cellular engineered living systems
- Source :
- APL Bioengineering, APL Bioengineering, Vol 2, Iss 4, Pp 040901-040901-21 (2018)
- Publication Year :
- 2018
- Publisher :
- AIP Publishing LLC, 2018.
-
Abstract
- Recent technological breakthroughs in our ability to derive and differentiate induced pluripotent stem cells, organoid biology, organ-on-chip assays, and 3-D bioprinting have all contributed to a heightened interest in the design, assembly, and manufacture of living systems with a broad range of potential uses. This white paper summarizes the state of the emerging field of “multi-cellular engineered living systems,” which are composed of interacting cell populations. Recent accomplishments are described, focusing on current and potential applications, as well as barriers to future advances, and the outlook for longer term benefits and potential ethical issues that need to be considered.
- Subjects :
- 0301 basic medicine
lcsh:Medical technology
Ethical issues
lcsh:Biotechnology
Biomedical Engineering
Biophysics
Bioengineering
Living systems
Biomaterials
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
White paper
Risk analysis (engineering)
lcsh:R855-855.5
lcsh:TP248.13-248.65
Induced pluripotent stem cell
030217 neurology & neurosurgery
Perspectives
Subjects
Details
- Language :
- English
- ISSN :
- 24732877
- Volume :
- 2
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- APL Bioengineering
- Accession number :
- edsair.doi.dedup.....4af58282b084e5537c71613683ca57db