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The Clinical and Histopathological Feature of Renal Manifestation of TAFRO Syndrome
- Source :
- Kidney International Reports
- Publication Year :
- 2020
- Publisher :
- Elsevier, 2020.
-
Abstract
- Introduction Thrombocytopenia, anasarca, myelofibrosis, renal dysfunction, and organomegaly (TAFRO) syndrome is a severe subtype of idiopathic multicentric Castleman’s disease, characterized by thrombocytopenia, anasarca, fever, reticulin myelofibrosis, and organomegaly. Renal complication of this disease can be life-threatening and sometimes requires hemodialysis, but it has not been elucidated in detail. Methods Case-series was designed to evaluate the renal histology of patients with TAFRO syndrome treated at our hospital. Results Seven patients were eligible to the criteria. All of them had severe diuretic-resistant anasarca and 6 of 7 had mild proteinuria (<br />Graphical abstract
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
030232 urology & nephrology
Mild proteinuria
030204 cardiovascular system & hematology
urologic and male genital diseases
Anasarca
Gastroenterology
Organomegaly
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Clinical Research
Internal medicine
medicine
Myelofibrosis
endotheliopathy
business.industry
Interleukin
TAFRO syndrome
medicine.disease
VEGF
Vascular endothelial growth factor
chemistry
Nephrology
Hemodialysis
medicine.symptom
Complication
business
Subjects
Details
- Language :
- English
- ISSN :
- 24680249
- Volume :
- 5
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Kidney International Reports
- Accession number :
- edsair.doi.dedup.....4ac298ed43782ba1a6c5e2f2519e1bba