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PERFUSION RESERVE OF CORONARY COLLATERAL CIRCULATION AND ITS SIGNIFICANCE IN THE DEVELOPMENT OF EXERCISE-INDUCED ISCHEMIA IN PATIENTS WITH MULTIVESSEL DISEASE
- Source :
- Japanese Circulation Journal. 58:15-21
- Publication Year :
- 1993
- Publisher :
- Japanese Circulation Society, 1993.
-
Abstract
- To assess the perfusion reserve of coronary collateral circulation, we analyzed exercise-stress tomographic thallium-201 myocardial images in 12 patients who had total occlusion in the right coronary artery (RCA) or left circumflex coronary artery (LCX) with well-developed collateral circulation and 90% stenosis in the left anterior descending coronary artery (LAD). In 6 of the 12 patients, the collateral circulation was non-jeopardized (group A). In the remaining 6 patients, the collateral circulation was jeopardized (group B). All 6 of the patients in group A had an exercise-induced decrease in thallium uptake in the segments supplied by the occluded RCA or LCX with collateral circulation, and 3 (50%) of these 6 also showed a decrease in thallium uptake in the segments supplied by the LAD. All 6 of the patients in group B also had an exercise-induced decrease in thallium uptake in the segments supplied by the occluded RCA or LCX with collateral circulation, but none showed a decrease in thallium uptake in the segments supplied by the LAD. In conclusion, the perfusion reserve of collateral circulation is equal to or less than 90% stenosis and myocardial ischemia occurs first in the collateralized segments during exercise in patients with jeopardized collateral circulation.
- Subjects :
- Adult
Male
medicine.medical_specialty
Physiology
Myocardial Ischemia
Ischemia
Collateral Circulation
chemistry.chemical_element
Coronary Disease
Anterior Descending Coronary Artery
Scintigraphy
Coronary artery disease
Coronary Circulation
medicine.artery
Internal medicine
medicine
Humans
cardiovascular diseases
Aged
Aged, 80 and over
medicine.diagnostic_test
business.industry
Heart
Middle Aged
medicine.disease
Collateral circulation
Stenosis
chemistry
Right coronary artery
Exercise Test
cardiovascular system
Cardiology
Thallium
Female
Cardiology and Cardiovascular Medicine
business
Tomography, Emission-Computed
Subjects
Details
- ISSN :
- 13474839 and 00471828
- Volume :
- 58
- Database :
- OpenAIRE
- Journal :
- Japanese Circulation Journal
- Accession number :
- edsair.doi.dedup.....4ab0c68db0e07e594dff6f9d8b44df00