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Creation of a Curated Aquatic Toxicology Database: EnviroTox
- Source :
- Environmental Toxicology and Chemistry
- Publication Year :
- 2019
- Publisher :
- John Wiley and Sons Inc., 2019.
-
Abstract
- Flexible, rapid, and predictive approaches that do not require the use of large numbers of vertebrate test animals are needed because the chemical universe remains largely untested for potential hazards. Development of robust new approach methodologies and nontesting approaches requires the use of existing information via curated, integrated data sets. The ecological threshold of toxicological concern (ecoTTC) represents one such new approach methodology that can predict a conservative de minimis toxicity value for chemicals with little or no information available. For the creation of an ecoTTC tool, a large, diverse environmental data set was developed from multiple sources, with harmonization, characterization, and information quality assessment steps to ensure that the information could be effectively organized and mined. The resulting EnviroTox database contains 91 217 aquatic toxicity records representing 1563 species and 4016 unique Chemical Abstracts Service numbers and is a robust, curated database containing high‐quality aquatic toxicity studies that are traceable to the original information source. Chemical‐specific information is also linked to each record and includes physico‐chemical information, chemical descriptors, and mode of action classifications. Toxicity data are associated with the physico‐chemical data, mode of action classifications, and curated taxonomic information for the organisms tested. The EnviroTox platform also includes 3 analysis tools: a predicted‐no‐effect concentration calculator, an ecoTTC distribution tool, and a chemical toxicity distribution tool. Although the EnviroTox database and tools were originally developed to support ecoTTC analysis and development, they have broader applicability to the field of ecological risk assessment. Environ Toxicol Chem 2019;9999:1–12. © 2019 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals, Inc. on behalf of SETAC.
- Subjects :
- Aquatic Organisms
Databases, Factual
Computer science
Health, Toxicology and Mutagenesis
Toxicological threshold of concern
Ecological threshold
010501 environmental sciences
computer.software_genre
Ecotoxicology
01 natural sciences
Risk Assessment
Field (computer science)
Environmental data
Aquatic toxicology
Set (abstract data type)
Database
03 medical and health sciences
Toxicity Tests, Acute
Environmental Chemistry
De minimis
Animals
Hazard/Risk Assessment
Aquatic toxicity
Environmental toxicology
Toxicity Tests, Chronic
030304 developmental biology
0105 earth and related environmental sciences
0303 health sciences
Information quality
Information source
computer
Water Pollutants, Chemical
Subjects
Details
- Language :
- English
- ISSN :
- 15528618 and 07307268
- Volume :
- 38
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Environmental Toxicology and Chemistry
- Accession number :
- edsair.doi.dedup.....4a9748597b15919621428d15c53b1122