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Probing the self-assembly and anti-glioblastoma efficacy of a cinnamoyl-capped dipeptide hydrogelator

Authors :
E. D. Sitsanidis
P. M. Kasapidou
J. R. Hiscock
V. Gubala
H. Castel
P. I. A. Popoola
A. J. Hall
A. A. Edwards
Publication Year :
2022
Publisher :
Royal Society of Chemistry, 2022.

Abstract

Herein, we introduce the first diphenylalanine dipeptide hydrogelator capped with the cinnamoyl functional group (Cin-L-F-L-F). We evaluate the effects of the cinnamoyl moiety on molecular self-assembly events and resultant physical properties of the hydrogel formed. In addition, we report our preliminary results of this dipeptide's cytotoxicity against glioblastoma (GBM) cancer cells. peerReviewed

Details

Language :
English
ISSN :
14770520
Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....4a7c09e3b432d418a5546d30944621bd