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Supplemental Figure S3 from Akt Inhibition Enhances Expansion of Potent Tumor-Specific Lymphocytes with Memory Cell Characteristics

Authors :
Nicholas P. Restifo
Douglas T. Fearon
Steven A. Rosenberg
Christopher A. Klebanoff
Mark S. Sundrud
Pawel Muranski
Luca Gattinoni
Francesco M. Marincola
Ena Wang
Nicolas Acquavella
Anthony Leonardi
Trevor Upham
Ryan D. Michalek
Sid P. Kerkar
Douglas C. Palmer
Zhiya Yu
Ken-ichi Hanada
Eric Tran
Robert L. Eil
Alena Gros
David Clever
Rahul Roychoudhuri
Madhusudhanan Sukumar
Joseph G. Crompton
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplemental Figure S3. Surface phenotype of Akti-treated and vehicle TIL isolated from patient with melanoma and expanded to clinical scale for 30 days prior to adoptive-transfer into humanized mouse model.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....4a6e19d2595f20315ab5195e6e0cdefb
Full Text :
https://doi.org/10.1158/0008-5472.22408149.v1