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Timing and Dose of Upper Limb Motor Intervention After Stroke: A Systematic Review
- Source :
- Stroke. 52:3706-3717
- Publication Year :
- 2021
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2021.
-
Abstract
- This systematic review aimed to investigate timing, dose, and efficacy of upper limb intervention during the first 6 months poststroke. Three online databases were searched up to July 2020. Titles/abstracts/full-text were reviewed independently by 2 authors. Randomized and nonrandomized studies that enrolled people within the first 6 months poststroke, aimed to improve upper limb recovery, and completed preintervention and postintervention assessments were included. Risk of bias was assessed using Cochrane reporting tools. Studies were examined by timing (recovery epoch), dose, and intervention type. Two hundred and sixty-one studies were included, representing 228 (n=9704 participants) unique data sets. The number of studies completed increased from one (n=37 participants) between 1980 and 1984 to 91 (n=4417 participants) between 2015 and 2019. Timing of intervention start has not changed (median 38 days, interquartile range [IQR], 22–66) and study sample size remains small (median n=30, IQR 20–48). Most studies were rated high risk of bias (62%). Study participants were enrolled at different recovery epochs: 1 hyperacute (
- Subjects :
- Advanced and Specialized Nursing
medicine.medical_specialty
business.industry
medicine.medical_treatment
Stroke Rehabilitation
Psychological intervention
Recovery of Function
medicine.disease
Time-to-Treatment
Upper Extremity
Systematic review
medicine.anatomical_structure
Sample size determination
Interquartile range
Intervention (counseling)
medicine
Physical therapy
Humans
Upper limb
Neurology (clinical)
Cardiology and Cardiovascular Medicine
Stroke recovery
business
Stroke
Subjects
Details
- ISSN :
- 15244628 and 00392499
- Volume :
- 52
- Database :
- OpenAIRE
- Journal :
- Stroke
- Accession number :
- edsair.doi.dedup.....4a6391d041a75829f630cc68b84f53fd