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UV-Crosslinked Electrospun Zein/PEO Fibroporous Membranes for Wound Dressing

Authors :
Medha Surendranath
Resmi Rajalekshmi
Rekha M. Ramesan
Prakash Nair
Ramesh Parameswaran
Source :
ACS Applied Bio Materials. 5:1538-1551
Publication Year :
2022
Publisher :
American Chemical Society (ACS), 2022.

Abstract

Electrospun zein membranes are suitable for various biomedical applications. A UV-crosslinked electrospun membrane of a zein/PEO blend for wound healing application was explored in this work. The improvement in mechanical properties of the membrane after UV crosslinking was attributed to the change in protein conformation from an α-helix to a β-sheet. The circular dichroism (CD) spectra and FTIR spectra confirmed this conformational change. XRD analysis was shown to prove the amorphous nature of polymer blends with specific broad peaks at 2θ = 9° and 20°. The water vapor transmission rate (WVTR) of the membrane was found to be in the range of 1500-2000 g m

Details

ISSN :
25766422
Volume :
5
Database :
OpenAIRE
Journal :
ACS Applied Bio Materials
Accession number :
edsair.doi.dedup.....4a60dcd6cb89315e546718c7b6945799
Full Text :
https://doi.org/10.1021/acsabm.1c01293