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A method of sterilizing and preserving fresh allograft heart valves
- Source :
- Thorax. 27:398-400
- Publication Year :
- 1972
- Publisher :
- BMJ, 1972.
-
Abstract
- The present study was undertaken to find an antibiotic mixture which would rapidly and completely sterilize a heavily contaminated allograft heart valve without reducing its viability. Two different antibiotic combinations were used; formula A was used for 66 valves and formula B for 60 valves. Viability of the valves was assessed by autoradiography and tissue culture, and was found to be similar in both formulae. Formula B proved more effective; all valves were sterile after 24 hours9 exposure to the antibiotics and remained so thereafter. The period of viability was greatly extended when a nutrient medium was used to store the valves.
- Subjects :
- Pulmonary and Respiratory Medicine
medicine.medical_specialty
Cell Survival
medicine.drug_class
business.industry
Antibiotics
Sterilization
Allograft heart
Articles
Fibroblasts
Heart Valves
Anti-Bacterial Agents
Culture Media
Surgery
Period of viability
Tissue culture
Antibiotic combinations
Culture Techniques
medicine
Autoradiography
Humans
Transplantation, Homologous
Tissue Preservation
business
Subjects
Details
- ISSN :
- 00406376
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Thorax
- Accession number :
- edsair.doi.dedup.....49f357e73b003783b115cc9ae75012f1