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Recent Trends of Polymer Mediated Liposomal Gene Delivery System
- Source :
- BioMed Research International, Vol 2014 (2014), BIOMED RESEARCH INTERNATIONAL
- Publication Year :
- 2014
- Publisher :
- Hindawi Limited, 2014.
-
Abstract
- Advancement in the gene delivery system have resulted in clinical successes in gene therapy for patients with several genetic diseases, such as immunodeficiency diseases, X-linked adrenoleukodystrophy (X-ALD) blindness, thalassemia, and many more. Among various delivery systems, liposomal mediated gene delivery route is offering great promises for gene therapy. This review is an attempt to depict a portrait about the polymer based liposomal gene delivery systems and their future applications. Herein, we have discussed in detail the characteristics of liposome, importance of polymer for liposome formulation, gene delivery, and future direction of liposome based gene delivery as a whole.
- Subjects :
- Drug compounding
Liposome
General Immunology and Microbiology
Blindness
business.industry
Genetic enhancement
lcsh:R
lcsh:Medicine
General Medicine
Transfection
Gene delivery
medicine.disease
Bioinformatics
General Biochemistry, Genetics and Molecular Biology
Nanocapsules
Dna genetics
medicine
business
Subjects
Details
- Language :
- English
- ISSN :
- 23146141 and 23146133
- Volume :
- 2014
- Database :
- OpenAIRE
- Journal :
- BioMed Research International
- Accession number :
- edsair.doi.dedup.....49f12d9e1033820faccbf58decebb73a