Back to Search
Start Over
Recent Treatment Patterns of Oropharyngeal Cancer in Korea Based on the Expert Questionnaire Survey of the Korean Society for Head and Neck Oncology (KSHNO)
- Source :
- Cancer Research and Treatment : Official Journal of Korean Cancer Association
- Publication Year :
- 2021
- Publisher :
- Korean Cancer Association, 2021.
-
Abstract
- Purpose The incidence of human papillomavirus (HPV)-related oropharyngeal cancer (OPC) has increased, and staging and optimal therapeutic approaches are challenging. A questionnaire survey was conducted to investigate the controversial treatment policy of stage T2 OPC according to the N category and determine the opinions of multidisciplinary experts in Korea.Materials and Methods Five OPC scenarios were developed by the Subcommittee on Oropharyngeal Treatment Guidelines of the Korean Society for Head and Neck Oncology and distributed to experts of multidisciplinary treatment hospitals.Results Sixty-five experts from 45 institutions responded. For the HPV-positive T2N0M0 scenario, 67.7% of respondents selected surgery followed by definitive concurrent chemoradiotherapy (CCRT) or radiotherapy alone. For the T2N1M0 HPV-positive scenario, there was a notable difference in the selection of primary treatment by expert specialty; 53.9% of respondents selected surgery and 39.8% selected definitive CCRT as the primary treatment. For the T2N3M0 advanced HPV-positive scenario, 50.0% of respondents selected CCRT and 33.3% considered induction chemotherapy (IC) as the primary treatment. CCRT and IC were significantly more frequently selected for the HPV-related OPC cases (p=0.010). The interdepartmental variability showed that the head and neck surgeons and medical oncologists favored surgery, whereas the radiation oncologists preferably selected definitive CCRT (p < 0.001).Conclusion In this study, surgery was preferred for lymph node-negative OPC, and as lymph node metastasis progressed, CCRT tended to be preferred, and IC was administered. Clinical practice patterns by stage and HPV status showed differences according to expert specialty. Multidisciplinary consensus guidelines will be essential in the future.
- Subjects :
- Male
0301 basic medicine
Human papillomavirus
Cancer Research
medicine.medical_specialty
Oropharyngeal neoploasms
Specialty
03 medical and health sciences
0302 clinical medicine
Robotic Surgical Procedures
Surveys and Questionnaires
Republic of Korea
Humans
Medicine
Practice Patterns, Physicians'
Stage (cooking)
Papillomaviridae
Treatment patterns
Aged
business.industry
General surgery
Incidence (epidemiology)
Papillomavirus Infections
Induction chemotherapy
Cancer
Questionnaire
Chemoradiotherapy
Middle Aged
Prognosis
medicine.disease
Head and Neck Cancer
Combined Modality Therapy
Oropharyngeal Neoplasms
030104 developmental biology
Oncology
030220 oncology & carcinogenesis
Questionnaire study
Carcinoma, Squamous Cell
Head and neck oncology
Original Article
Female
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 20059256 and 15982998
- Volume :
- 53
- Database :
- OpenAIRE
- Journal :
- Cancer Research and Treatment
- Accession number :
- edsair.doi.dedup.....49eb1a7aa1a9deab1daf4956a524cb58