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Placental mesenchymal dysplasia: a case report
- Source :
- Case Reports in Obstetrics and Gynecology, Case Reports in Obstetrics and Gynecology, Vol 2012 (2012)
- Publication Year :
- 2012
-
Abstract
- Introduction. A rare case of histologically proven placental mesenchymal dysplasia (PMD) with fetal omphalocele in a 22-year-old patient is reported.Material and Methods. Antenatal ultrasound of this patient showed hydropic placenta with a live fetus of 17 weeks period of gestation associated with omphalocele. Cordocentesis detected the diploid karyotype of the fetus. Patient, when prognosticated, choose to terminate the pregnancy in view of high incidence of fetal and placental anomalies. Subsequent histopathological examination of placenta established the diagnosis to be placental mesenchymal dysplasia.Conclusion. On clinical and ultrasonic grounds, suspicion of P.M.D. arises when hydropic placenta with a live fetus presents in second trimester of pregnancy. Cordocentesis can detect the diploid karyotype of the fetus in such cases. As this condition is prognostically better than triploid partial mole, continuation of pregnancy can sometimes be considered after through antenatal screening and patient counseling. However, a definite diagnosis of P.M.D. is made only on placental histology by absence of trophoblast hyperplasia and trophoblastic inclusions.
- Subjects :
- Gynecology
medicine.medical_specialty
Pregnancy
Fetus
Omphalocele
Obstetrics
business.industry
Obstetrics and Gynecology
Trophoblast
Hydropic placenta
Case Report
medicine.disease
lcsh:Gynecology and obstetrics
Placental Mesenchymal Dysplasia
medicine.anatomical_structure
Placenta
embryonic structures
medicine
Gestation
business
lcsh:RG1-991
reproductive and urinary physiology
Subjects
Details
- ISSN :
- 20906692
- Volume :
- 2012
- Database :
- OpenAIRE
- Journal :
- Case reports in obstetrics and gynecology
- Accession number :
- edsair.doi.dedup.....495673e021a27c8322ab04b1ef8627cf