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Relationship between clinical and radiological signs of bronchiectasis in COPD patients: Results from COSYCONET
- Source :
- Respiratory medicine. 172
- Publication Year :
- 2020
-
Abstract
- Bronchiectasis (BE) might be frequently present in COPD but masked by COPD symptoms. We studied the relationship of clinical signs of bronchiectasis to the presence and extent of its radiological signs in patients of different COPD severity. Visit 4 data (GOLD grades 1-4) of the COSYCONET cohort was used. Chest CT scans were evaluated for bronchiectasis in 6 lobes using a 3-point scale (0: absence, 1: ≤50%, 2: >50% BE-involvement for each lobe). 1176 patients were included (61%male, age 67.3y), among them 38 (3.2%) with reported physicians' diagnosis of bronchiectasis and 76 (6.5%) with alpha1-antitrypsin deficiency (AA1D). CT scans were obtained in 429 patients. Within this group, any signs of bronchiectasis were found in 46.6% of patients, whereby ≤50% BE occurred in 18.6% in ≤2 lobes, in 10.0% in 3-4 lobes, in 15.9% in 5-6 lobes; >50% bronchiectasis in at least 1 lobe was observed in 2.1%. Scores ≥4 correlated with an elevated ratio FRC/RV. The clinical diagnosis of bronchiectasis correlated with phlegm and cough and with radiological scores of at least 3, optimally ≥5. In COPD patients, clinical diagnosis and radiological signs of BE showed only weak correlations. Correlations became significant with increasing BE-severity implying radiological alterations in several lobes. This indicates the importance of reporting both presence and extent of bronchiectasis on CT. Further research is warranted to refine the criteria for CT scoring of bronchiectasis and to determine the relevance of radiologically but not clinically detectible bronchiectasis and their possible implications for therapy in COPD patients.
- Subjects :
- Pulmonary and Respiratory Medicine
Male
medicine.medical_specialty
Copd patients
Medizin
Comorbidity
Severity of Illness Index
Pulmonary Disease, Chronic Obstructive
Medicine
Humans
In patient
Lung
Aged
Aged, 80 and over
COPD
Bronchiectasis
business.industry
Phlegm
Middle Aged
medicine.disease
Radiological weapon
Clinical diagnosis
Cohort
Female
Radiography, Thoracic
Radiology
medicine.symptom
business
Tomography, X-Ray Computed
Subjects
Details
- ISSN :
- 15323064
- Volume :
- 172
- Database :
- OpenAIRE
- Journal :
- Respiratory medicine
- Accession number :
- edsair.doi.dedup.....48e5b6c01c11916bc7c8fddc1d90ef89