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Utility of fluorodeoxyglucose positron emission tomography/computed tomography in patients with fever of unknown origin diagnosed as lymphoma
- Source :
- Medical Principles and Practice
- Publication Year :
- 2014
-
Abstract
- Objective: To assess the efficacy of fluorine-18 fluorodeoxyglucose positron emission tomography (18F-FDG PET)/computed tomography (CT) in the diagnosis of patients with fever of unknown origin (FUO), who were finally diagnosed as lymphoma. Subjects and Methods: A retrospective study was performed in the First Affiliated Hospital, School of Medicine of Zhejiang University, China, from March 2009 to March 2012. The PET/CT images of consecutive patients with FUO were analyzed. Within 1 week of PET/CT scanning, additional histological tests were also performed if clinically needed. Results: A total of 73 consecutive patients were included. Of these, 34 (47%) had a PET/CT finding suggestive of the presence of lymphoma and 29 (85%) had a diagnosis of confirmed lymphoma; 39 (53%) had a PET/CT result revealing the absence of lymphoma and 4 (10%) were diagnosed by biopsy as having lymphoma, . The most frequent lymphoma diagnosis was peripheral T cell lymphoma (n = 16; 55%), followed by diffuse large B cell lymphoma (n = 9; 31%). The accuracy of PET/CT was 88%. Conclusion: In this study, PET/CT had high diagnostic accuracy in patients with FUO resulting from lymphoma, which indicated that PET/CT scanning was a valuable diagnostic tool for these groups of patients with FUO.
- Subjects :
- Adult
Male
medicine.medical_specialty
China
Positron emission tomography
Adolescent
Lymphoma
Computed tomography
Multimodal Imaging
Young Adult
Fluorodeoxyglucose F18
Predictive Value of Tests
hemic and lymphatic diseases
Biopsy
Diagnosis
medicine
Humans
Fever of unknown origin
Aged
Retrospective Studies
Original Paper
medicine.diagnostic_test
business.industry
Retrospective cohort study
General Medicine
Middle Aged
medicine.disease
Peripheral T-cell lymphoma
Positron-Emission Tomography
Female
Radiology
Radiopharmaceuticals
business
Nuclear medicine
Tomography, X-Ray Computed
Diffuse large B-cell lymphoma
Subjects
Details
- ISSN :
- 14230151
- Volume :
- 23
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Medical principles and practice : international journal of the Kuwait University, Health Science Centre
- Accession number :
- edsair.doi.dedup.....48e152d7a1fa5f80d2b3287e46ce353e