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Effect of repeated oral infection of hamsters with scrapie
- Source :
- Journal of General Virology. 79:609-612
- Publication Year :
- 1998
- Publisher :
- Microbiology Society, 1998.
-
Abstract
- The development of a transmissible spongiform encephalopathy upon uptake of the infectious agent in feed was studied in the model system scrapie in hamsters. Compared to single dosing, repeated dosing caused disease at a considerable higher incidence. The risk of infection was higher when the time interval between repetitive dosing was short. There was a statistically significant trend of clearance of infectivity with time.
Details
- ISSN :
- 14652099 and 00221317
- Volume :
- 79
- Database :
- OpenAIRE
- Journal :
- Journal of General Virology
- Accession number :
- edsair.doi.dedup.....486eae1a5e84928049ec0120e620fc98