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Data set on a study of gene expression in peripheral samples to identify biomarkers of severity of allergic and nonallergic asthma

Authors :
David Calzada
Joaquín Quiralte
Joaquín Sastre
Fernando Florido
Selene Baos
Blanca Cárdaba
Carlos Lahoz
Lucía Cremades
[Baos,S
Calzada,D
Cremades,L
Lahoz,C
Cárdaba,B] Immunology Department, IIS- Jiménez Díaz Foundation, UAM, Madrid, Spain. [Baos,S
Sastre,J
Cárdaba,B] CIBERES, CIBER of Respiratory Diseases, Spain. [Sastre,J] Allergy Department, Jiménez Díaz Foundation, Madrid, Spain. [Quiralte,J] Allergy Department, Vírgen del Rocío University Hospital, Seville, Spain. [Florido,F] Allergy Department, San Cecilio University Hospital, Granada, Spain.
[Baos, Selene] UAM, IIS Jimenez Diaz Fdn, Immunol Dept, Madrid, Spain
[Calzada, David] UAM, IIS Jimenez Diaz Fdn, Immunol Dept, Madrid, Spain
[Cremades, Lucia] UAM, IIS Jimenez Diaz Fdn, Immunol Dept, Madrid, Spain
[Lahoz, Carlos] UAM, IIS Jimenez Diaz Fdn, Immunol Dept, Madrid, Spain
[Cardaba, Blanca] UAM, IIS Jimenez Diaz Fdn, Immunol Dept, Madrid, Spain
[Sastre, Joaquin] CIBERES, CIBER Resp Dis, Madrid, Spain
[Lahoz, Carlos] CIBERES, CIBER Resp Dis, Madrid, Spain
[Cardaba, Blanca] CIBERES, CIBER Resp Dis, Madrid, Spain
[Sastre, Joaquin] Jimenez Diaz Fdn, Allergy Dept, Madrid, Spain
[Quiralte, Joaquin] Virgen del Rocio Univ Hosp, Allergy Dept, Seville, Spain
[Florido, Fernando] San Cecilio Univ Hosp, Allergy Dept, Granada, Spain
FEDER
CIBERES (ISCIII)
Biobank from the Fund for Health Research (Spanish Ministry of Economy and Competitiveness)
Conchita Rabago Foundation
MINECO
European Social Fund (ESF)
Youth Employment Initiative (YEI)
Source :
Data in Brief, Data in Brief, Vol 10, Iss C, Pp 505-510 (2017)
Publication Year :
2017
Publisher :
Elsevier BV, 2017.

Abstract

This article contains information related to the research article entitled "Biomarkers associated with disease severity in allergic and nonallergic asthma" (S. Baos, D. Calzada, L. Cremades, J. Sastre, J. Quiralte, F. Florido, C. Lahoz, B. Cárdaba, In press). Specifically, the clinical criteria stablished for selecting the study population (n=104 subjects) are described. Moreover, this article describes the criteria for selecting the 94 genes to be analyzed in PBMCs (peripheral blood mononuclear cells), it is provided a description of these genes and a Table with the genes most differentially expressed by clinical phenotypes and, finally it is detailed the experimental methodology followed for studying the protein expression of MSR1 (macrophage scavenger receptor 1), one of the genes evaluated in the research. This work was supported in part by research grants PI13/01730 co-supported by FEDER, CIBERES (ISCIII, 0013) and Biobank (PT13/0010/0012) from the Fund for Health Research (Spanish Ministry of Economy and Competitiveness). S. Baos was supported by CIBERES (ISCIII, 0013) and Conchita Rábago Foundation. D. Calzada by Conchita Rábago Foundation, Madrid, Spain. L. Cremades was supported by a contract from MINECO (PEJ-2014-A-31609, Sistema de Garantía Juvenil), cofinanced by European Social Fund (ESF) and Youth Employment Initiative (YEI). Yes

Details

ISSN :
23523409
Volume :
10
Database :
OpenAIRE
Journal :
Data in Brief
Accession number :
edsair.doi.dedup.....48659c1956fc09c845a39d153a0a6a84
Full Text :
https://doi.org/10.1016/j.dib.2016.12.035