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Data set on a study of gene expression in peripheral samples to identify biomarkers of severity of allergic and nonallergic asthma
- Source :
- Data in Brief, Data in Brief, Vol 10, Iss C, Pp 505-510 (2017)
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- This article contains information related to the research article entitled "Biomarkers associated with disease severity in allergic and nonallergic asthma" (S. Baos, D. Calzada, L. Cremades, J. Sastre, J. Quiralte, F. Florido, C. Lahoz, B. Cárdaba, In press). Specifically, the clinical criteria stablished for selecting the study population (n=104 subjects) are described. Moreover, this article describes the criteria for selecting the 94 genes to be analyzed in PBMCs (peripheral blood mononuclear cells), it is provided a description of these genes and a Table with the genes most differentially expressed by clinical phenotypes and, finally it is detailed the experimental methodology followed for studying the protein expression of MSR1 (macrophage scavenger receptor 1), one of the genes evaluated in the research. This work was supported in part by research grants PI13/01730 co-supported by FEDER, CIBERES (ISCIII, 0013) and Biobank (PT13/0010/0012) from the Fund for Health Research (Spanish Ministry of Economy and Competitiveness). S. Baos was supported by CIBERES (ISCIII, 0013) and Conchita Rábago Foundation. D. Calzada by Conchita Rábago Foundation, Madrid, Spain. L. Cremades was supported by a contract from MINECO (PEJ-2014-A-31609, Sistema de Garantía Juvenil), cofinanced by European Social Fund (ESF) and Youth Employment Initiative (YEI). Yes
- Subjects :
- 0301 basic medicine
Allergy
Diseases::Respiratory Tract Diseases::Bronchial Diseases::Asthma [Medical Subject Headings]
Phenomena and Processes::Genetic Phenomena::Phenotype [Medical Subject Headings]
Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biochemistry::Proteomics [Medical Subject Headings]
Leucocitos mononucleares
Sistema mononuclear fagocítico
lcsh:Computer applications to medicine. Medical informatics
Peripheral blood mononuclear cell
MSR1
03 medical and health sciences
0302 clinical medicine
Gene expression
Chemicals and Drugs::Biological Factors::Biological Markers [Medical Subject Headings]
medicine
Receptores depuradores
lcsh:Science (General)
Gene
Asma
Anatomy::Hemic and Immune Systems::Immune System::Mononuclear Phagocyte System [Medical Subject Headings]
Data Article
Asthma
Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Scavenger [Medical Subject Headings]
Multidisciplinary
business.industry
Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear [Medical Subject Headings]
medicine.disease
Phenotype
Biomarcadores
Proteómica
030104 developmental biology
Immunology
Peripheral samples
lcsh:R858-859.7
Population study
business
Biomarkers
lcsh:Q1-390
030215 immunology
Subjects
Details
- ISSN :
- 23523409
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Data in Brief
- Accession number :
- edsair.doi.dedup.....48659c1956fc09c845a39d153a0a6a84
- Full Text :
- https://doi.org/10.1016/j.dib.2016.12.035