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Transport of Calcium Ions into Mitochondria
- Source :
- Current Genomics
- Publication Year :
- 2016
- Publisher :
- Bentham Science Publishers, 2016.
-
Abstract
- To uptake calcium ions of mitochondria is of significant functional connotation for cells, because calcium ions in mitochondria are involved in energy production, regulatory signals transfer, and mitochondrial permeability transition pore opening and even programmed cell death of apoptosis, further playing more roles in plant productivity and quality. Cytoplasmic calcium ions access into outer mitochondrial membrane (OMM) from voltage dependent anion-selective channel (VDAC) and were absorbed into inner mitochondrial membrane (IMM) by mitochondrial calcium uniporter (MCU), rapid mitochondrial calcium uptake (RaM) or mitochondrial ryanodine receptor (mRyR). Although both mitochondria and the mechanisms of calcium transport have been extensively studied, but there are still long-standing or even new challenges. Here we review the history and recent discoveries of the mitochondria calcium ions channel complex involved calcium assimilation, and discuss the role of calcium ions into mitochondria.
- Subjects :
- 0301 basic medicine
biology
chemistry.chemical_element
Calcium
Mitochondrial apoptosis-induced channel
Calcium in biology
Article
Mitochondria
Calcium ATPase
03 medical and health sciences
Mitochondrial membrane transport protein
030104 developmental biology
chemistry
Mitochondrial permeability transition pore
Biochemistry
Channels
Genetics
Biophysics
biology.protein
Calcium ions uptake
Uniporter
Mitochondrial calcium uptake
Genetics (clinical)
Calcium signaling
Subjects
Details
- Language :
- English
- ISSN :
- 18755488 and 13892029
- Volume :
- 17
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Current Genomics
- Accession number :
- edsair.doi.dedup.....485cf57b86146f02fd3505f7e2d64431