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A cluster of invasive meningococcal disease (IMD) caused by Neisseria meningitidis serogroup W among university students, France, February to May 2017

Authors :
Christian Merle
Eva Hong
Ibrahim Mounchetrou Njoya
Daniel Lévy-Bruhl
Anne-Sophie Barret
Muhamed-Kheir Taha
Clément Bassi
CIRE- Ile de France
Centre National de Référence des Méningocoques et Haemophilus influenzae - National Reference Center Meningococci and Haemophilus influenzae (CNR)
Institut Pasteur [Paris]
Agence Régionale de la Santé (ARS)
Santé publique France - French National Public Health Agency [Saint-Maurice, France]
We wish to thank Asmahan Batapou and Léoine Pierre, members of Public Health unit of the Health Agency in the Ile-de-France region and Annie-Claude Paty, member of the French Institute for Public Health Surveillance, who helped us to collect information. We are also grateful for the genomic platform PIBNEt-P2M of the Institut Pasteur. The publication also made use of the Meningitis Research Foundation Meningococcus Genome Library (http://www.meningitis.org/research/genome) developed by Public Health England, the Wellcome Trust Sanger Institute and the University of Oxford as a collaboration.
Institut Pasteur [Paris] (IP)
Source :
Eurosurveillance, Eurosurveillance, European Centre for Disease Prevention and Control, 2017, 22 (28), pii=30574. ⟨10.2807/1560-7917.ES.2017.22.28.30574⟩, Eurosurveillance, 2017, 22 (28), pii=30574. ⟨10.2807/1560-7917.ES.2017.22.28.30574⟩
Publication Year :
2017
Publisher :
European Centre for Disease Control and Prevention (ECDC), 2017.

Abstract

International audience; Between February and May 2017, two cases of invasive meningococcal disease caused by a new, rapidly expanding serogroup W meningococci variant were reported among students of an international university in Paris. Bacteriological investigations showed that isolates shared identical genotypic formula (W:P1.5,2:F1–1:cc11) and belonged to the South American/UK lineage. A vaccination campaign was organised that aimed at preventing new cases linked to potential persistence of the circulation of the bacteria in the students.

Subjects

Subjects :
Male
0301 basic medicine
Epidemiology
MESH: Meningococcal Infections/blood
Neisseria meningitidis
medicine.disease_cause
MESH: Genotype
Molecular typing
0302 clinical medicine
Medicine
030212 general & internal medicine
cluster
MESH: Molecular Typing
Neisseria meningitidis serogroup
MESH: Paris
South American/UK strain
3. Good health
MESH: Meningococcal Infections/diagnosis
MESH: Neisseria meningitidis, Serogroup W-135/isolation & purification
Vaccination
Invasive meningococcal disease
MESH: Young Adult
South american
MESH: Whole Genome Sequencing
Rapid Communication
Paris
Fever
Genotype
education
MESH: Meningococcal Infections/microbiology
030106 microbiology
Serogroup
Disease cluster
Microbiology
MESH: Contact Tracing
Young Adult
03 medical and health sciences
Neisseria meningitidis, Serogroup W-135
university
Virology
Humans
serogroup W
Students
MESH: Humans
Whole Genome Sequencing
MESH: Neisseria meningitidis, Serogroup W-135/genetics
business.industry
invasive meningococcal disease
Public Health, Environmental and Occupational Health
MESH: Serogroup
MESH: Fever/etiology
MESH: Male
Meningococcal Infections
Molecular Typing
MenACWY conjugate vaccine
MESH: Students
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Contact Tracing
business
Contact tracing

Details

ISSN :
15607917 and 1025496X
Volume :
22
Database :
OpenAIRE
Journal :
Eurosurveillance
Accession number :
edsair.doi.dedup.....47c67ab5790bf9e69ee6b6631ece2fa0

Tools

Authors Abstract Subjects Details