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Impact of a short exposure to levofloxacin on faecal densities and relative abundance of total and quinolone-resistant Enterobacteriaceae
- Source :
- Clinical Microbiology and Infection. 22:646.e1-646.e4
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- Emergence of resistant Enterobacteriaceae in the intestinal microbiota during antibiotic treatment is well documented but its early dynamic is not. Here, we compared the densities of total Enterobacteriaceae and relative abundance (RA) of quinolone-resistant Enterobacteriaceae (QRE) in the first stool passed by patients who had a short exposure to levofloxacin (levofloxacin, n=12) or not (control, n=8). Mean densities (SD) (log CFU/g stool) of total Enterobacteriaceae were lower in the levofloxacin group than in the control group-3.4 (1.6) versus 6.7 (1.7), respectively, p
- Subjects :
- Male
0301 basic medicine
Microbiology (medical)
Veterinary medicine
medicine.drug_class
030106 microbiology
Antibiotics
Levofloxacin
Biology
Microbiology
Feces
03 medical and health sciences
Antibiotic resistance
Enterobacteriaceae
Drug Resistance, Bacterial
medicine
Humans
Relative species abundance
General Medicine
Quinolone
biology.organism_classification
Bacterial Load
Anti-Bacterial Agents
Gastrointestinal Microbiome
Infectious Diseases
Female
Short exposure
medicine.drug
Subjects
Details
- ISSN :
- 1198743X
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Clinical Microbiology and Infection
- Accession number :
- edsair.doi.dedup.....479982858722f521e92424d831444d41