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MRI of the left atrium: predicting clinical outcomes in patients with atrial fibrillation

Authors :
Nazem Akoum
Rob S. MacLeod
Christopher J. McGann
Marcos Daccarett
Nassir F. Marrouche
Source :
Expert review of cardiovascular therapy. 9(1)
Publication Year :
2010

Abstract

Atrial fibrillation is a significant public health burden, with clinically, epidemiologically and economically significant repercussions. In the last decade, catheter ablation has provided an improvement in morbidity and quality of life, significantly reducing long-term healthcare costs and avoiding recurrences compared with drug therapy. Despite recent progress in techniques, current catheter ablation success rates fall short of expectations. Late gadolinium-enhancement cardiovascular MRI is a well-established tool to image the myocardium and, most specifically, the left atrium. Unique imaging protocols allow for left atrial structural remodeling and fibrosis assessment, which has been demonstrated to correlate with clinical outcomes after catheter ablation, assessment of the individual's risks of thromboembolic events, and effective imaging of patients with left atrial appendage thrombus. Late gadolinium-enhancement MRI aids in the individualized treatment of atrial fibrillation, stratifying recurrence risk and guiding specific ablation strategies. Real-time MRI offers significant safety and effectiveness profiles that would optimize the invasive treatment of atrial fibrillation.

Details

ISSN :
17448344
Volume :
9
Issue :
1
Database :
OpenAIRE
Journal :
Expert review of cardiovascular therapy
Accession number :
edsair.doi.dedup.....478a5c702df11d6ef23ce89a4a00a4ef