Additional file 4: of CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice

Brain cytokines and tau and plasma neurofilament-light. The carbonate-soluble fraction of brain homogenates were assayed for (a) inflammatory cytokines including IL-1β, IL-6, and TNF-α and (b) total tau, p-tau at Thr231, and the ratio of p-tau to total tau. c Plasma levels of neurofilament-light at 8 M post-injury is also reported. In (a), data are plotted as median ± interquartile range. In (b) and (c), data are plotted as mean ± SE. (PDF 50 kb)