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Advances in Imaging Reactive Oxygen Species
- Source :
- Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol 62, iss 4, J Nucl Med
- Publication Year :
- 2020
- Publisher :
- Society of Nuclear Medicine, 2020.
-
Abstract
- Reactive oxygen species (ROS) play a pivotal role in many cellular processes and can be either beneficial or harmful. The design of ROS-sensitive fluorophores has allowed for imaging of specific activity and has helped elucidate mechanisms of action for ROS. Understanding the oxidative role of ROS in the many roles it plays allows us to understand the human body. This review provides a concise overview of modern advances in the field of ROS imaging. Indeed, much has been learned about the role of ROS throughout the years; however, it has recently been shown that using nanoparticles, rather than individual small organic fluorophores, for ROS imaging can further our understanding of ROS.
- Subjects :
- 1.1 Normal biological development and functioning
Clinical Sciences
Bioengineering
02 engineering and technology
010402 general chemistry
01 natural sciences
animal imaging
Focus on Molecular Imaging
Underpinning research
Humans
chromophores
Nanotechnology
Radiology, Nuclear Medicine and imaging
chemistry.chemical_classification
Reactive oxygen species
Animal imaging
Chemistry
imaging
ROS
molecular imaging
radicals
021001 nanoscience & nanotechnology
Molecular Imaging
0104 chemical sciences
Cell biology
Nuclear Medicine & Medical Imaging
Generic health relevance
Reactive Oxygen Species
0210 nano-technology
Subjects
Details
- ISSN :
- 2159662X and 01615505
- Volume :
- 62
- Database :
- OpenAIRE
- Journal :
- Journal of Nuclear Medicine
- Accession number :
- edsair.doi.dedup.....4765cad10381285e06f848f0b121dcdd
- Full Text :
- https://doi.org/10.2967/jnumed.120.245415