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Dynamic changes in marital status and survival in women with breast cancer: a population-based study
- Source :
- Scientific Reports, Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
- Publication Year :
- 2020
-
Abstract
- Marital status proved to be an independent prognostic factor for survival in patients with breast cancer. We therefore strove to explore the impact of dynamic changes in marital status on the prognosis of breast cancer patients. We selected patients meeting the eligibility criteria from the Surveillance, Epidemiology, and End Results cancer database. We then used multivariate Cox proportional hazard regression model to analyze the effect of dynamic changes in marital status on the prognosis of overall survival (OS) and breast cancer-specific special survival (BCSS). Compared with the patients in the Single–Single group and the divorced/separated/widowed–divorced/separated/widowed (DSW–DSW) group, patients in the Married–Married group were significantly associated with better BCSS (HR 1.13, 95% CI: 1.03–1.19, P P P P P = 0.660; HR 1.06, 95% CI: 0.97–1.15, P = 0.193, respectively) but better OS (HR 1.14, 95% CI: 1.09–1.19, P P P = 0.003) but no difference in OS (HR 1.08, 95% CI: 0.98–1.18, P = 0.102); In contrast to the Married–DSW group, the Married–Married group exhibited better BCSS (HR 1.11, 95% CI: 1.05–1.18, P P
- Subjects :
- End results
Adult
Prognostic factor
medicine.medical_specialty
Disease-free survival
Science
Breast Neoplasms
Kaplan-Meier Estimate
Models, Biological
Article
03 medical and health sciences
0302 clinical medicine
Breast cancer
Internal medicine
Epidemiology
Medicine
Humans
In patient
030212 general & internal medicine
Retrospective Studies
Multidisciplinary
Marital Status
business.industry
Cancer
Middle Aged
medicine.disease
Population based study
Survival Rate
030220 oncology & carcinogenesis
Marital status
Female
business
Subjects
Details
- ISSN :
- 20452322
- Volume :
- 11
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific reports
- Accession number :
- edsair.doi.dedup.....474e4b1b219655fd19e6f5782af300ee