Features of premature infants immune system

Aryaev N. L., Marichereda V. G., Shevchenko I. M., Moskalenko T. Ya., El Mezevgi J. M., Shevchenko N. V. Features of premature infants immune system. Journal of Education, Health and Sport. 2017;7(5):647-653. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.816283 http://ojs.ukw.edu.pl/index.php/johs/article/view/4562 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author (s) 2017; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 05.05.2017. Revised: 23.05.2017. Accepted: 31.05.2017. FEATURES OF PREMATURE INFANTS IMMUNE SYSTEM N. L. Aryaev1, V. G. Marichereda1, I. M. Shevchenko1, T. Ya. Moskalenko2, J. M. El Mezevgi1, N. V. Shevchenko2 1 Odessa National Medical University, Odessa, Ukraine. 2 Maternity hospital № 7, Odessa, Ukraine e-mail: valmar@i.ua Abstract Premature birth (PB) is the most important aspects in maternal and child health care. The frequency of PB and birth of immature infants is increasing and ranges from 4.0 to 15.0-20.0%. In Ukraine its frequency varies from 3.0% to 12.0%. Preterm infants account for 60-70% of early neonatal and 65-75% of infant mortality. The aim: to examine the main premature baby’s immune system indexes as it is the immune system state that determines survival of a newborn child, the peculiarity of its life in neonatal period, effectiveness of therapeutic and rehabilitation measures, as well as the degree of disability. There were two groups of premature children under study: the I group, n = 62 premature infants, the age of gestation 34-36 weeks without perinatal pathology. The IId group (control ) was represented by 15 healthy newborns, aged 38-40 weeks of gestation. The study was carried out in the first 3 days of the child's life by flow cytofluorometry. In premature infants, the immaturity of the immune system was noted in the form of decrease in all indices of nonspecific immunity: the level of the complement component of C3, the level of immunoglobulins class A, G and M and the values of T-killers and B-lymphocytes. Key words: premature birth, premature child immune system, indexes of immune system.