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Cerebrospinal fluid glutamate changes in functional movement disorders
- Source :
- NPJ Parkinson's Disease
- Publication Year :
- 2020
-
Abstract
- The aim of this study was to assess cerebrospinal fluid (CSF) concentrations of specific amino acids using a high-performance liquid chromatography system in a sample of patients with functional movement disorders (FMDs) and in a sample of controls. CSF levels of glutamate were significantly lower in patients with FMD than in controls. This finding argues in favor of glutamatergic dysfunction in the pathophysiology of FMD.
- Subjects :
- medicine.medical_specialty
Parkinson's disease
Brief Communication
03 medical and health sciences
Cellular and Molecular Neuroscience
Glutamatergic
0302 clinical medicine
Cerebrospinal fluid
Internal medicine
medicine
In patient
Neurodegeneration
chemistry.chemical_classification
business.industry
Glutamate receptor
Diagnostic markers
medicine.disease
Pathophysiology
030227 psychiatry
Amino acid
Endocrinology
Neurology
chemistry
Neurology (clinical)
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 23738057
- Volume :
- 6
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- NPJ Parkinson's disease
- Accession number :
- edsair.doi.dedup.....473cf3251383bdf55cde096ad980b80a