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Forced oscillatory parameters as predictors of COPD assessment test improvement in untreated COPD patients
- Source :
- Respiratory physiologyneurobiology. 296
- Publication Year :
- 2021
-
Abstract
- Background Few studies have examined whether baseline spirometry and the forced oscillation technique (FOT) would predict The COPD Assessment Test (CAT) score improvement after treatment of untreated COPD patients. Methods The study subjects included 65 untreated COPD patients. They underwent the CAT, spirometry, and FOT (MostGraph) before and after treatment for more than 2 months. In addition, recursive partitioning analysis was performed using spirometry and the FOT parameters to identify the predictors of CAT improvement (CAT score ≥2). Results CAT scores and lung function significantly improved after treatment. Recursive partitioning analysis identified 3 improved classes, defined by Rrs at 20 Hz (R20), Xrs at 5 Hz (X5), and ΔX5, but not by spirometry. The accuracy of predicting CAT improvement was as follows: odds ratio, 25.3; 95 % confidence interval, 6.1 to 104.1; sensitivity, 91.2 %; specificity, 71.0 %; positive likelihood ratio, 3.14; and negative likelihood ratio, 0.12. Conclusions FOT helps predict improved health status in untreated COPD patients.
- Subjects :
- Pulmonary and Respiratory Medicine
Spirometry
Adult
Male
medicine.medical_specialty
Physiology
Copd patients
Recursive partitioning
Likelihood ratios in diagnostic testing
Sensitivity and Specificity
Severity of Illness Index
Pulmonary Disease, Chronic Obstructive
Internal medicine
Forced Expiratory Volume
Oscillometry
Outcome Assessment, Health Care
Medicine
Humans
Aged
medicine.diagnostic_test
business.industry
General Neuroscience
Minimal clinically important difference
Odds ratio
Middle Aged
Confidence interval
Respiratory Function Tests
Copd assessment test
Cardiology
Female
business
Subjects
Details
- ISSN :
- 18781519
- Volume :
- 296
- Database :
- OpenAIRE
- Journal :
- Respiratory physiologyneurobiology
- Accession number :
- edsair.doi.dedup.....4732ff373f38b55d422418f29067de22