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Avengers against cancer: A new era of nano-biomaterial-based therapeutics
- Source :
- Materials Today. 51:317-349
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Cancer is one of the leading causes of death worldwide. As the cancer burden continues to increase globally, it exerts tremendous physical, emotional, and financial strain on individuals, families, communities, and health care systems. Cancer can affect any part of the body and is characterized by its uncontrollable growth. Numerous treatments, such as radiation therapy and chemotherapy which utilize various drugs, are currently in use; however, their harmful side effects and the development of drug resistance have resulted in major roadblocks when treating cancer. With advancements in synthetic and polymer chemistry, the use of nanoparticle-based drug delivery systems and chemotherapeutic macromolecules have garnered increasing attention in the previous decade. This review discusses the recent advancements in the use of nanoparticle-based drug delivery systems as well as the development of synthetic biodegradable polypeptides and polymers for cancer treatment (both in vivo and in vitro). Additionally, we outline the potent selectivity and efficacy for immunotherapies and bacteria-based therapies that are used to treat various cancers.
- Subjects :
- Cationic polymers
business.industry
Mechanical Engineering
medicine.medical_treatment
Polypeptides
Cancer
Drug resistance
Condensed Matter Physics
medicine.disease
Bioinformatics
Bacteria therapy
Cancer treatment
Radiation therapy
Nanomedicine
Mechanics of Materials
Drug delivery
medicine
Financial strain
Cancer burden
General Materials Science
Immunotherapy
business
Subjects
Details
- ISSN :
- 13697021
- Volume :
- 51
- Database :
- OpenAIRE
- Journal :
- Materials Today
- Accession number :
- edsair.doi.dedup.....46e8b2b0d93dca35230e4e4071f700d1