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A Novel Prognostic Signature of mRNA-lncRNA in Breast Cancer

Authors :
Yi Fang
Qiang Liu
Jing Wang
Yihang Qi
Zhongzhao Wang
Xiangyu Wang
Xiangyi Kong
Ran Gao
Source :
DNA and cell biology. 39(4)
Publication Year :
2020

Abstract

Comprehensive genomic testing will be required to identify appropriate targets for the precision therapy of breast cancer. Although RNA sequencing (RNA-seq) is an unparalleled platform for this purpose, existing molecular-based prognostic signatures are not optimal for RNA-seq data. In this study, we analyzed RNA-seq datasets to generate a novel prognostic gene signature for breast cancer patients. RNA-seq and clinical datasets from breast cancer patients were obtained from The Cancer Genome Atlas and randomly assigned to training (

Details

ISSN :
15577430
Volume :
39
Issue :
4
Database :
OpenAIRE
Journal :
DNA and cell biology
Accession number :
edsair.doi.dedup.....46e7a4c04226623e37e9e7e5166da6c8