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An Optical Nanoruler Based on a Conjugated Polymer−Silver Nanoprism Pair for Label-Free Protein Detection
- Source :
- Advanced Materials. 27:6040-6045
- Publication Year :
- 2015
- Publisher :
- Wiley, 2015.
-
Abstract
- An optical nanoruler system based on a conjugated polyelectrolyte-silver nanoprism pair is developed for label-free protein detection by taking advantage of the metal-enhanced fluorescence effect of silver nanostructures. Antibody-antigen interactions induce a change in the metal-fluorophore distance, followed by the response of a fluorescent signal of the conjugated polyelectrolyte. The system is used to detect target antigens sensitively and selectively.
- Subjects :
- Materials science
Nanostructure
Polymers
Nanotechnology
Conjugated system
Photochemistry
Fluorescence
Protein detection
Electrolytes
Nanoruler
Microscopy, Electron, Transmission
Humans
General Materials Science
Antigens
Label free
chemistry.chemical_classification
Spectrum Analysis
Mechanical Engineering
Optical Devices
Proteins
Silver Compounds
Equipment Design
Polymer
Conjugated Polyelectrolytes
Nanostructures
chemistry
Mechanics of Materials
MCF-7 Cells
Microscopy, Electron, Scanning
Subjects
Details
- ISSN :
- 09359648
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Advanced Materials
- Accession number :
- edsair.doi.dedup.....46e70c54f06884c31132b12e1db6ff02