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Evaluation of Pulmonary Hypertension Using <scp>4D</scp> Flow <scp>MRI</scp>
- Source :
- Journal of Magnetic Resonance Imaging. 56:234-245
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- BACKGROUND Cardiac magnetic resonance imaging (MRI) is becoming an alternative to right heart catheterization (RHC) for evaluating pulmonary hypertension (PH). A need exists to further evaluate cardiac MRI's ability to characterize PH. PURPOSE To evaluate the potential for four-dimensional (4D) flow MRI-derived pulmonary artery velocities to characterize PH. STUDY TYPE Prospective case-control. POPULATION Fifty-four PH patients (56% female); 25 controls (36% female). FIELD STRENGTH/SEQUENCE 1.5 T; gradient recalled echo 4D flow and balanced steady-state free precession cardiac cine. ASSESSMENT RHC was used to derive patients' pulmonary vascular resistance (PVR). 4D flow measured blood velocities at the main, left, and right pulmonary arteries (MPA, LPA, and RPA); cine measured ejection fraction, end diastolic, and end systolic volumes (EF, EDV, and ESV). EDV and ESV were normalized (indexed) to body surface area (ESVI and EDVI). Parameters were evaluated between, and within, PH subgroups: pulmonary arterial hypertension (PAH); PH due to left heart disease (PH-LHD)/chronic lung disease (PH-CLD)/or chronic thrombo-emboli (CTE-PH). STATISTICAL TESTS Analysis of variance and Kruskal-Wallis tests compared parameters between subgroups. Pearson's r assessed velocity, PVR, and volume correlations. Significance definition: P
- Subjects :
- Male
medicine.medical_specialty
Hypertension, Pulmonary
Population
Diastole
Pulmonary Artery
Cardiac magnetic resonance imaging
Internal medicine
medicine.artery
medicine
Humans
Radiology, Nuclear Medicine and imaging
education
Body surface area
Pulmonary Arterial Hypertension
education.field_of_study
Ejection fraction
medicine.diagnostic_test
business.industry
medicine.disease
Magnetic Resonance Imaging
Pulmonary hypertension
medicine.anatomical_structure
Pulmonary artery
Vascular resistance
Cardiology
Female
Vascular Resistance
business
Subjects
Details
- ISSN :
- 15222586 and 10531807
- Volume :
- 56
- Database :
- OpenAIRE
- Journal :
- Journal of Magnetic Resonance Imaging
- Accession number :
- edsair.doi.dedup.....46c265c03592c887d918557224cb9c18