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Restoring function after spinal cord injury: towards clinical translation of experimental strategies
- Source :
- The Lancet. Neurology. 13(12)
- Publication Year :
- 2014
-
Abstract
- Spinal cord injury is currently incurable and treatment is limited to minimising secondary complications and maximising residual function by rehabilitation. Improved understanding of the pathophysiology of spinal cord injury and the factors that prevent nerve and tissue repair has fuelled a move towards more ambitious experimental treatments aimed at promoting neuroprotection, axonal regeneration, and neuroplasticity. By necessity, these new options are more invasive. However, in view of recent advances in spinal cord injury research and demand from patients, clinicians, and the scientific community to push promising experimental treatments to the clinic, momentum and optimism exist for the translation of candidate experimental treatments to clinical spinal cord injury. The ability to rescue, reactivate, and rewire spinal systems to restore function after spinal cord injury might soon be within reach.
- Subjects :
- medicine.medical_specialty
Rehabilitation
Neuronal Plasticity
business.industry
Regeneration (biology)
medicine.medical_treatment
Recovery of Function
Tissue repair
medicine.disease
Decompression, Surgical
Spinal cord injury research
Neuroprotection
Surgical methods
Physical medicine and rehabilitation
Medicine
Animals
Humans
Neurology (clinical)
business
Spinal cord injury
Embryonic Stem Cells
Spinal Cord Injuries
Subjects
Details
- ISSN :
- 14744465
- Volume :
- 13
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- The Lancet. Neurology
- Accession number :
- edsair.doi.dedup.....46bc94b93b3b51985480055b75ed397f