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Electrochemical Tattoo Biosensors for Real-Time Noninvasive Lactate Monitoring in Human Perspiration
- Source :
- Analytical Chemistry. 85:6553-6560
- Publication Year :
- 2013
- Publisher :
- American Chemical Society (ACS), 2013.
-
Abstract
- The present work describes the first example of real-time noninvasive lactate sensing in human perspiration during exercise events using a flexible printed temporary-transfer tattoo electrochemical biosensor that conforms to the wearer's skin. The new skin-worn enzymatic biosensor exhibits chemical selectivity toward lactate with linearity up to 20 mM and demonstrates resiliency against continuous mechanical deformation expected from epidermal wear. The device was applied successfully to human subjects for real-time continuous monitoring of sweat lactate dynamics during prolonged cycling exercise. The resulting temporal lactate profiles reflect changes in the production of sweat lactate upon varying the exercise intensity. Such skin-worn metabolite biosensors could lead to useful insights into physical performance and overall physiological status, hence offering considerable promise for diverse sport, military, and biomedical applications.
- Subjects :
- Adult
Male
Tattooing
integumentary system
Chemistry
Sweating
Biosensing Techniques
Electrochemical Techniques
Analytical Chemistry
Young Adult
Computer Systems
Physical performance
Sweat analysis
medicine
Exercise intensity
Humans
Electrochemical biosensor
Female
Lactic Acid
Epidermis
Perspiration
medicine.symptom
Sweat
Biosensor
Biomedical engineering
Subjects
Details
- ISSN :
- 15206882 and 00032700
- Volume :
- 85
- Database :
- OpenAIRE
- Journal :
- Analytical Chemistry
- Accession number :
- edsair.doi.dedup.....46b8beb44f2e4e46f20a9c513384a5a4