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Novel hybrid vesicles co-assembled from a cationic lipid and PAAc-g-mPEG with pH-triggered transmembrane channels for controlled drug release
- Source :
- Chemical communications (Cambridge, England). 47(39)
- Publication Year :
- 2011
-
Abstract
- This work presents an important example of novel hybrid vesicles with pH-triggered transmembrane channels prepared by co-assembly of poly(acrylic acid)-g-poly(monomethoxy ethylene glycol) (PAAc-g-mPEG) with a cationic lipid, didodecyldimethylammonium bromide (DDAB), via electrostatic interaction for effective doxorubicin (DOX) release.
- Subjects :
- Models, Molecular
Acrylic Resins
Molecular Conformation
Micelle
Catalysis
Polyethylene Glycols
chemistry.chemical_compound
Materials Chemistry
Copolymer
Organic chemistry
Particle Size
Acrylic acid
Transmembrane channels
Drug Carriers
Vesicle
Cell Membrane
Metals and Alloys
Cationic polymerization
General Chemistry
Hydrogen-Ion Concentration
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Quaternary Ammonium Compounds
Membrane
chemistry
Doxorubicin
Delayed-Action Preparations
Ceramics and Composites
Biophysics
Ethylene glycol
Subjects
Details
- ISSN :
- 1364548X
- Volume :
- 47
- Issue :
- 39
- Database :
- OpenAIRE
- Journal :
- Chemical communications (Cambridge, England)
- Accession number :
- edsair.doi.dedup.....46a5478dbad5afb1b1553db64081b4ea