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A real-world, cross sectional study of oral lesions and their association with CD4 cell counts and HIV viral load in Yunnan, China
- Source :
- Medicine
- Publication Year :
- 2020
- Publisher :
- Lippincott Williams & Wilkins, 2020.
-
Abstract
- Human immunodeficiency virus (HIV) supresses immune system, primarily cell-mediated immunity. Cluster of differentiation 4 (CD4) cell count, viral load, and oral lesions are the most important laboratory parameters to evaluate the evolution of acquired immunodeficiency syndrome. The present study aims to determine the incidence of HIV-related oral lesions with CD4 cell count and viral load in Yunnan, China. A cross-sectional study was conducted from December 2007 to December 2009, in 1812 HIV positive patients from Department of Infectious Diseases in Kunming Third People's Hospital. CD4, CD8, and viral load data were collected and analyzed statistically using SPSS 11.3. Out of 1812 HIV positive patients, 929 (51.27%) were associated with 1 or more oral lesions. The most common oral lesions observed were Candida Pseudomembranous (13.75%), Candida erythematous (10.93%), Oral hairy leukoplakia (7.95%), Aphthous ulcer (6.18%), Herpes simplex infection (5.58%). In most patients with oral lesions, the CD4 cell count was 200/μL and with undetectable (P 500/μL (P
- Subjects :
- Adult
Male
medicine.medical_specialty
China
HIV-viral load
Observational Study
HIV Infections
Gastroenterology
03 medical and health sciences
Young Adult
0302 clinical medicine
Immune system
Acquired immunodeficiency syndrome (AIDS)
Immunity
highly active antiretroviral therapy (HAART)
Internal medicine
Antiretroviral Therapy, Highly Active
medicine
Humans
030212 general & internal medicine
Oral hairy leukoplakia
Acquired Immunodeficiency Syndrome
Cluster of differentiation
business.industry
Incidence (epidemiology)
General Medicine
Middle Aged
Viral Load
medicine.disease
CD4
CD4 Lymphocyte Count
stomatognathic diseases
human immunodeficiency virus (HIV)
Cross-Sectional Studies
030220 oncology & carcinogenesis
oral lesions
aphthous ulcer
Female
business
Mouth Diseases
Viral load
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 15365964 and 00257974
- Volume :
- 99
- Issue :
- 40
- Database :
- OpenAIRE
- Journal :
- Medicine
- Accession number :
- edsair.doi.dedup.....460def62c1e1f0561629302c2582caa7