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CORRELATION OF MECHANICAL IMAGING AND HISTOPATHOLOGY OF RADICAL PROSTATECTOMY SPECIMENS: A PILOT STUDY FOR DETECTING PROSTATE CANCER
CORRELATION OF MECHANICAL IMAGING AND HISTOPATHOLOGY OF RADICAL PROSTATECTOMY SPECIMENS: A PILOT STUDY FOR DETECTING PROSTATE CANCER
- Source :
- Journal of Urology. 160:797-801
- Publication Year :
- 1998
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 1998.
-
Abstract
- A new modality termed mechanical imaging has recently been developed. We determined whether mechanical imaging could be used to detect prostate cancer in radical prostatectomy specimens.Stress patterns on the surface of excised prostates were evaluated using the data obtained from a planar piezoelectric resistive force sensor array. Seven radical prostatectomy and 2 cystoprostatectomy specimens were manually palpated and evaluated by the mechanical imager. The prostates were histopathologically analyzed for the presence of cancer. The results of the manual palpation, mechanical imaging and pathological analysis were correlated.Mechanical imaging correlated closely with nodules palpated in all specimens and in 1 it revealed a suspicious area undetected by palpation, which on subsequent histological analysis demonstrated carcinoma.Mechanical imaging can detect areas of heterogeneity in prostate tissue which correlate with cancer. Our findings provide the basis for the development of a transrectal mechanical imaging probe for prostate cancer detection.
- Subjects :
- Male
medicine.medical_specialty
Pathology
Urology
medicine.medical_treatment
Pilot Projects
Palpation
Cystoprostatectomy
Prostate cancer
Prostate
Humans
Medicine
Aged
Prostatectomy
medicine.diagnostic_test
business.industry
Prostatic Neoplasms
Cancer
Middle Aged
medicine.disease
medicine.anatomical_structure
Adenocarcinoma
Histopathology
Radiology
business
Subjects
Details
- ISSN :
- 15273792 and 00225347
- Volume :
- 160
- Database :
- OpenAIRE
- Journal :
- Journal of Urology
- Accession number :
- edsair.doi.dedup.....4609a376c0fb3b702e6189802c84843c
- Full Text :
- https://doi.org/10.1016/s0022-5347(01)62790-3