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Homology modeling, model and software evaluation: three related resources
- Source :
- Bioinformatics. 14:523-528
- Publication Year :
- 1998
- Publisher :
- Oxford University Press (OUP), 1998.
-
Abstract
- MOTIVATION: Homology modeling is rapidly becoming the method of choice for obtaining three-dimensional coordinates for proteins because genome projects produce sequences at a much higher rate than NMR and X-ray laboratories can solve the three-dimensional structures. The quality of protein models will not be immediately clear to novices and support with the evaluation seems to be needed. Expert users are sometimes interested in evaluating the quality of modeling programs rather than the quality of the models themselves. RESULTS: Three servers have been made available to the scientific community: a homology modeling server, a model quality evaluation server and a server that evaluates models built of proteins for which the structure is already known, thereby implicitly evaluating the quality of the modeling program. AVAILABILITY: The modeling-related servers and several structure analysis servers are freely available at http://swift.embl-heidelberg.de/servers/ CONTACT: gert.vriend@embl-heidelberg.de
- Subjects :
- Models, Molecular
Statistics and Probability
Software Evaluation
Databases, Factual
Computer science
media_common.quotation_subject
Biochemistry
Homology (biology)
Software
Server
Quality (business)
Homology modeling
Homology (anthropology)
Molecular Biology
media_common
Structure (mathematical logic)
Internet
Sequence Homology, Amino Acid
business.industry
Computational Biology
Proteins
Reproducibility of Results
Genome project
Computer Science Applications
Computational Mathematics
Computational Theory and Mathematics
Artificial intelligence
Software engineering
business
Subjects
Details
- ISSN :
- 13674811 and 13674803
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- Bioinformatics
- Accession number :
- edsair.doi.dedup.....45fdb047b0ca06dcd0196930768e908a