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Enhancer-derived RNA: A Primer
- Source :
- Genomics, Proteomics & Bioinformatics, Genomics, Proteomics & Bioinformatics, Vol 15, Iss 3, Pp 196-200 (2017)
- Publication Year :
- 2017
- Publisher :
- Elsevier, 2017.
-
Abstract
- Enhancer-derived RNAs (eRNAs) are a group of RNAs transcribed by RNA polymerase II from the domain of transcription enhancers, a major type of cis-regulatory elements in the genome. The correlation between eRNA production and enhancer activity has stimulated studies on the potential role of eRNAs in transcriptional regulation. Additionally, eRNA has also served as a marker for global identification of enhancers. Here I review the brief history and fascinating properties of eRNAs.
- Subjects :
- 0301 basic medicine
Transcriptional Activation
RNA, Untranslated
eRNA
Enhancer RNAs
RNA polymerase II
Review
Biochemistry
03 medical and health sciences
Transcription (biology)
Genetics
Transcriptional regulation
Animals
Humans
Enhancer
Non-coding RNA
Promoter Regions, Genetic
Molecular Biology
Transcription factor
lcsh:QH301-705.5
biology
RNA
High-Throughput Nucleotide Sequencing
Gene regulation
Computational Mathematics
030104 developmental biology
Enhancer Elements, Genetic
lcsh:Biology (General)
Gene Expression Regulation
biology.protein
Next-generation sequencing
Transcription Factors
Subjects
Details
- Language :
- English
- ISSN :
- 22103244 and 16720229
- Volume :
- 15
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Genomics, Proteomics & Bioinformatics
- Accession number :
- edsair.doi.dedup.....45e6f6447ee714bf233e9aeae9f8cfb7