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Long-term Survival After Surgical Treatment of Spinal Metastasis - The Predictive Role of Sex
- Source :
- Anticancer research. 40(3)
- Publication Year :
- 2020
-
Abstract
- BACKGROUND/AIM An increasing number of patients undergo surgical treatment for metastatic spinal cord compression (MSCC). However, the possible role of sex as an independent predictor of long-term survival has not been studied. This study aimed to examine whether sex is associated with long-term survival after surgical treatment in patients with MSCC. PATIENTS AND METHODS A total of 110 patients were operated on for MSCC from 2005 through 2006. The relation between sex and overall survival was investigated. The follow-up period was 10 years. RESULTS Survival time was significantly longer for women compared to men (mean±SD: 29±5.2 vs. 14±3.6 month (p=0.01). With adjusted analysis, this difference remained statistically significant. After adjusting for specific primary tumor type and time since surgery, the hazard-ratio of 10-year survival for men compared to women was 1.47 (95% confidence intervaI=1.01-2.18, p=0.048). CONCLUSION These findings indicate that sex is associated with long-term survival in patients treated for MSCC.
- Subjects :
- Male
Cancer Research
medicine.medical_specialty
Independent predictor
Cohort Studies
03 medical and health sciences
0302 clinical medicine
Sex Factors
Cancer Survivors
Internal medicine
Long term survival
Metastatic spinal cord compression
Overall survival
medicine
Humans
In patient
Prospective Studies
Surgical treatment
Spinal Neoplasms
business.industry
General Medicine
Middle Aged
medicine.disease
Prognosis
Primary tumor
Oncology
030220 oncology & carcinogenesis
Spinal metastasis
Female
business
Spinal Cord Compression
Subjects
Details
- ISSN :
- 17917530
- Volume :
- 40
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Anticancer research
- Accession number :
- edsair.doi.dedup.....45e403acf1eb1d361b535f1812edb271