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Deep convolution neural networks to differentiate between <scp>COVID</scp> ‐19 and other pulmonary abnormalities on chest radiographs: Evaluation using internal and external datasets
- Source :
- International Journal of Imaging Systems and Technology
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- We aimed to evaluate the performance of convolutional neural networks (CNNs) in the classification of coronavirus disease 2019 (COVID‐19) disease using normal, pneumonia, and COVID‐19 chest radiographs (CXRs). First, we collected 9194 CXRs from open datasets and 58 from the Korea University Anam Hospital (KUAH). The number of normal, pneumonia, and COVID‐19 CXRs were 4580, 3884, and 730, respectively. The CXRs obtained from the open dataset were randomly assigned to the training, tuning, and test sets in a 70:10:20 ratio. For external validation, the KUAH (20 normal, 20 pneumonia, and 18 COVID‐19) dataset, verified by radiologists using computed tomography, was used. Subsequently, transfer learning was conducted using DenseNet169, InceptionResNetV2, and Xception to identify COVID‐19 using open datasets (internal) and the KUAH dataset (external) with histogram matching. Gradient‐weighted class activation mapping was used for the visualization of abnormal patterns in CXRs. The average AUC and accuracy of the multiscale and mixed‐COVID‐19Net using three CNNs over five folds were (0.99 ± 0.01 and 92.94% ± 0.45%), (0.99 ± 0.01 and 93.12% ± 0.23%), and (0.99 ± 0.01 and 93.57% ± 0.29%), respectively, using the open datasets (internal). Furthermore, these values were (0.75 and 74.14%), (0.72 and 68.97%), and (0.77 and 68.97%), respectively, for the best model among the fivefold cross‐validation with the KUAH dataset (external) using domain adaptation. The various state‐of‐the‐art models trained on open datasets show satisfactory performance for clinical interpretation. Furthermore, the domain adaptation for external datasets was found to be important for detecting COVID‐19 as well as other diseases.
- Subjects :
- Domain adaptation
Artificial neural network
Coronavirus disease 2019 (COVID-19)
business.industry
Deep learning
Radiography
Histogram matching
computer‐aided diagnosis (CAD)
deep learning
chest radiography
Convolutional neural network
Electronic, Optical and Magnetic Materials
Convolution
COVID‐19
Computer Vision and Pattern Recognition
Artificial intelligence
Electrical and Electronic Engineering
business
Nuclear medicine
Research Articles
Software
Research Article
lung diseases
Mathematics
Subjects
Details
- ISSN :
- 10981098 and 08999457
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- International Journal of Imaging Systems and Technology
- Accession number :
- edsair.doi.dedup.....45dd68fd709b6a04a99be0de4fa49c77